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Was 67 kg (range: 48?03 kg). There were 13 Caucasians, three Thais, one Black, one Asian Indian, one Mulatto and one Cape Coloured. PK parameters are presented in Figure 1. The mean half-life and mean clearance remained largely unchanged after repeated daily dosing for 14 or 28 days. There was no accumulation of MICA between day 1 and the end of therapy beyond that expected for a drug with linear
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